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NNMT metabolizes nicotinamide into 1-methylnicotinamide (MNA), diverting it away from the NAD+ salvage pathway

Chia, Y

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Hygroscopic, Refrigerator, under inert atmosphere solubility DMSO (Slightly), Methanol (Slightly) form Solid pka 9.830.15(Predicted) color White to Off-White Sequence Hexanoyl-Tyr-Ile-Ahx-NH2 InChIKey ADWKPLXLPNPJTR-JTJYXVOQSA-N SMILES C(N)(=O)[C@H]([C@@H](C)CC)N(C(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)CCCCC)CCCCCC(N)=O Description Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met